Reduce cardiovascular The ultimate public health goal of anti hypertensive therapy is to and renal mortality. Since most persons with hypertension,
especially those who are 50years of age, will reach the DBP goal once the SBP
goal is achieved, the primary focus should be on attaining the SBP goal.
Treating SBP and DBP to targets that are <140/90mmHg is associated with a
decrease in CVD complications. In patient with hypertension and diabetes or
renal disease, the BP goal is <130/80 mm Hg.
In clinical trials, anti hypertensive therapy has been associated
with reductions in (1) stroke incidence, averaging 35-40 percent,(2) myocardial
infarction (Mi),averaging 20-25 percent, and (3) heart failure, averaging>50
percent. It is estimated that in patients with stage1 hypertension and
additional cardiovascular risk factors, achieving a sustained 12 mm Hg reduction
in SBP over 10 years will prevent 1 death for every 11 patients treated. In the
added presence of CVD or target organ damage, only nine patients would require
such BP to prevent one death.More Details
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